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ABSTRACT Introduction: Modern EEG technology can evaluate the current level of an individual's central functioning after analyzing the frequency of brain waves (II). The A wave (8 ~ 14Hz) of brain waves (EBG) is one of the most important index parameters in diagnosing the brain's central functioning level. Objective: To explore the effects of different training loads on the brain function of elite archers and provide an objective basis for improving the scientific level of archery training. Methods: The effects of EEG information and central nerve transmitters on athletes' regulation and training were analyzed by testing and statistical methods. Results: Both HL-LLI and LL-HLI stages showed a decreasing trend in EEG complexity. Although the differences between the two stages were not significant all of them were considerably lower than the LL-LLI stage. The number of athletes with central fatigue in both stages showed an increasing trend. Conclusions: Athletes in training also need to focus on recovery after training, which requires a view of scientific training and scientific recovery as an organic whole that cannot be separated. Level of evidence II; Therapeutic studies - investigation of treatment results.
RESUMO Introdução: A moderna tecnologia do EEG pode avaliar o nível atual do funcionamento central de indivíduos ao analisar a frequência de ondas cerebrais (II). A onda A (8 ~ 14Hz) de ondas cerebrais (EBG) é um dos parâmetros indicadores mais importantes no diagnóstico do nível de funcionamento central do cérebro. Objetivo: Explorar os efeitos de diferentes cargas de treinamento na função cerebral de arqueiros de elite e fornecer uma base objetiva para melhorar o nível científico de treinamento de arca e flecha. Métodos: Os efeitos de informações do EEG e da transmissão de nervos centrais na regulação e no treinamento de atletas foram analisados através de testes e métodos estatísticos. Resultados: Tanto a fase HL-LLI quanto a LL-HLI demonstraram uma tendência decrescente na complexidade do EEG. Apesar das diferenças entre as duas fases não serem significativas, todas eram consideravelmente mais baixas do que a fase LL-LLI. O número de atletas com fadiga central nas duas fases demonstrou uma tendência crescente. Conclusões: Atletas em treinamento devem também ficar atentos à recuperação após o treinamento, o que exige uma visão de treinamento científico e recuperação cientifica como um todo orgânico que não pode ser separado. Nível de evidência II; Estudos terapêuticos - investigação de resultados de tratamento.
Resumen Introducción: La moderna tecnología del EEG puede evaluar el nivel actual del funcionamiento central de individuos al analizar la frecuencia de ondas cerebrales (II). La onda A (8 ~ 14Hz) de ondas cerebrales (EBG) es uno de los parámetros indicadores más importantes en el diagnóstico del nivel de funcionamiento central del cerebro. Objetivo: Explorar los efectos de diferentes cargas de entrenamiento en la función cerebral de arqueros de élite y brindar una base objetiva para mejorar el nivel científico de entrenamiento de arco y flecha. Métodos: Los efectos de informaciones del EEG y de la transmisión de nervios centrales en la regulación y en el entrenamiento de atletas se analizaron a través de pruebas y métodos estadísticos. Resultados: Tanto la fase HL-LLI como la LL-HLI demostraron una tendencia decreciente en la complejidad del EEG. Pese a que las diferencias entre las dos fases no sean significativas, todas eran considerablemente más bajas que la fase LL-LLI. El número de atletas con fatiga central en las dos fases demostró una tendencia creciente. Conclusiones: Atletas en entrenamiento deben también atentarse a la recuperación tras el entrenamiento, que exige una visión de entrenamiento científico y recuperación científica como un todo orgánico que no puede separarse. Nivel de evidencia II; Estudios terapéuticos - investigación de resultados de tratamiento.
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Objective@#To observe the preventive effect of alkaline drinking water on hyperuricemia in mice. @*Methods@#Sixty male SPF Kunming mice were randomly divided into six groups: pH 7.3, pH 8.0, pH 9.3 intervention groups, in which the mice were given water with pH values of 7.3±0.5, 8.0±0.5 and 9.3±0.6, respectively; the control group, model group and positive drug group ( with 2 g/L allopurinol ) were given double distilled water. Except for the control group, the mice in each group were given yeast by gavage (1.5 g/mL) for 13 days. On the 14th day, the mice were injected with 300 mg/kg potassium oxyzinate by intraperitoneal injection, and then fasted for 1 day. On the 16th day, serum uric acid, creatinine and urea nitrogen were detected, and renal tissues were stained to observe the morphology.The expression levels of neutrophil gelatinase-associated lipocalin ( NGAL ), tissue inhibitor of metalloproteinase 1( TIMP1 ), organic anion transporter 1 ( OAT1 ) and urate transporter 1 ( URAL-1 ) in renal tissues were determined bywestern blotting. The mRNA expression levels of URAL-1 and OAT1 were detected by real-time fluorescent quantita⁃tive polymerase chain reaction.@*Results@#The level of serum uric acid was higher in the model group than in the control group and in the pH 9.3 intervention group (both P<0.05). The number and area of renal tubular lesions were less in the pH 9.3 intervention group than in the model group (all P<0.05). The relative expression levels of NGAL and URAT-1 proteins were lower in the pH 9.3 intervention group than in the model group, and the relative expression level of OAT1 protein was higher in the pH 9.3 intervention group than in the model group ( all P<0.05). The relativeexpression level of URAT-1 mRNA was lower in the pH 9.3 intervention group than in the model group, and the rela⁃tive expression level of OAT1 mRNA was higher in the pH 9.3 intervention group than in the model group ( all P<0.05 ).@*Conclusion@#Alkaline drinking water with pH value of 9.3±0.6 can effectively prevent hyperuricemia and acute kidney injury in mice.
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<p><b>OBJECTIVE</b>To compare the clinical results of early and delayed intramedullary nailing and locked plating for the treatment of multi-segments tibial fractures of type AO/ASIF-42C2.</p><p><b>METHODS</b>Between January 2010 and January 2013,45 patients with multi-segments closed tibial fractures of AO/ASIF-42C2 were treated by early primary intramedullary nailing and locked plating in 20 cases as early group and delayed in 25 cases as delayed group. In early group,20 cases included 13 males and 7 females with an average age of (37.9±14.3) years old ranging from 20 to 56 years;according to soft tissue injury Tscherne classification, 8 fractures were frade I,12 were grade II. In delayed group, 25 cases included 17 males and 8 females with an average age of (38.7±17.2) years old ranging from 24 to 55 years,4 fractures were grade I ,19 were grade II ,2 were grade III. The operative time, blood loss, hospital stay,fracture healing time and complications were recorded. At final follow-up, the Johner-Wruhs score were used to evaluate functional efficacy, and the posterior-anterior and lateral X-ray to evaluate fracture reduction and alignment.</p><p><b>RESULTS</b>All the patients were followed up for (12.5±2.5) months in early group and (13.2±2.8) months in delayed group (P>0.05). No wounds infections were happened. At the last follow-up, the mean range of knee joint was 10°-0°-120°. According to Johner-Wruhs scoring,there were 15 cases in excellent,3 in good,fair in 2 in early group; 21 in excellent,2 in good,2 in fair. The average operative time,blood loss had no significant differences between two groups (P>0.05), but hospital stay in early group was significantly shorter than those in delayed group(P<0.05). Average fracture healing time of early group and delayed group were (5.3±2.6) months and (6.0±2.9) months, respectively (P>0.05).</p><p><b>CONCLUSION</b>For multi-segments tibial fractures of type AO/ASIF-42C2 with preoperative minor soft tissue injuries lighter of Tscherne grade I or II, early primary intramedullary nailing and locked plating does not significantly increase the postoperative incidence of soft tissue complications for patients. The early and delayed primary intramedullary nailing and locked plating for treatment of AO/ASIF-42C2 proximal third tibial fractures can get similar curative effect.</p>